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Elemental Organic Chemistry 1

525-3 Elemental Organic Chemistry 1 Materials and Chemistry S5
Lessons : 14 h TD : 14 h TP : 12 h Project : 0 h Total : 40 h
Co-ordinator : Jacques Rouden
Prerequisite
General chemistry and organic chemistry: notions of kinetics and thermodynamics, Lewis representations, functions, isomeria, basic stereochemistry, chemical bonding, hybridization, molecule geometry, nomenclature, representation molecules
Course Objectives
This teaching enables the acquisition of the fundamental concepts necessary for the learning of organic chemistry. Some basic reactions (aliphatic nucleophile substitutions, additions on alcene and alcynes, eliminations) are also discussed.
Syllabus
- Stereochemistry (conformational and configurational)
- The chemical reaction. electronic effects, acid-based reaction, nucleophilia and electrophilia, reaction intermediates, energy profile of a reaction, activation and catalysis, solvents, large reaction classes
- Nucleophile substitution (SN1 and SN2) and synthetic applications
- Elimination (E1, E2, E1CB)
- Additions on multiple links (electrophilic additions, apolar additions, Diels-Alder reaction)
Practical work (TD or TP)
TD: exercises on the structure and reactivity of organic molecules in conjunction with the concepts discussed in the course
TP: acquisition of basic techniques from the organic chemistry laboratory.
Acquired skills
Basic knowledge of the organic compounds needed to study the diversity of reactions and reaction mechanisms involved in organic chemistry.
Bibliography
Chimie Organique : Tout le cours en fiches, J Maddaluno et al., Dunod, 2ème ed. 2016
Traité de chimie organique, K. Peter C. Vollhardt, N. E. Shore, DeBoeck, 1999
Chimie Organique, J. Clayden, N. Greeves, S. Warren, P. Wothers, DeBoeck, 2003.

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